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Alzheimer's disease is a progressive, degenerative disease. Symptoms include loss of memory, judgment and reasoning; difficulty with day-to-day tasks; and changes in communication abilities, mood and behaviour. If you notice any of these symptoms, it is important to see your doctor.

Why find out?

Symptoms of Alzheimer's disease can be similar to symptoms of other conditions such as depression, thyroid or heart disease, infections, drug interactions or alcohol abuse.

Finding out the cause of the symptoms can help people:

understand the source of the symptoms
get the proper care, treatment and support
plan for the future
the earlier a treatment can be given, the better the result - and new treatments are on the way

Making the diagnosis

There is currently no single test that can tell if a person has Alzheimer's disease. The diagnosis is made through a systematic assessment which eliminates other possible causes. Until the time when there is a conclusive test, doctors may continue to use the words "probable Alzheimer's disease". However, you should be aware that doctors making this diagnosis are accurate 80 to 90 per cent of the time.

Making the diagnosis can take time. The diagnosis can be made in a family doctor's office, a memory clinic or a hospital. The doctor may or may not feel that the person needs to see a number of health-care professionals to help make the diagnosis. These may include a psychologist, psychiatrist, neurologist, geriatrician, nurse, social worker or occupational therapist. They will look for problems with the person's memory, reasoning ability, language and judgment, and how these affect day-to-day function.

The process involves:

Medical history
Both the individual and family members or friends will be asked questions regarding the person's symptoms now and in the past. There will be questions about past illnesses and about family medical and psychiatric history.

Mental status exam
This part of the process tests the person's sense of time and place as well as the ability to remember, express herself and do simple calculations. It may involve exercises such as recalling words and objects, drawing and spelling, and questions such as "What year is it?"

Physical exam
To help rule out other causes, a physical exam will be done. The doctor will look for heart, lung, liver, kidney or thyroid problems that may be causing the symptoms. To evaluate whether other nervous system disorders are causing the symptoms, the doctor will test muscle tone and strength, co-ordination, eye movement, speech and sensation.

Laboratory tests
A number of tests will be done. Detailed blood work will be ordered to help detect problems such as anemia, diabetes, thyroid problems or infections that might be contributing to the symptoms.

Other tests such as X-rays and EEG's (electroencephalogram) may be used to determine the source of the problem. In some centres, scans may be used. The following may be recommended, but are not always necessary for a diagnosis:

- CT (computerized tomography) scan and MRI (magnetic resonance imaging) take images of the brain.

- SPECT (single proton emission computed tomography) shows how blood is circulating to the brain.

- PET (positive electron tomography) shows how the different areas of the brain respond during certain activities such as reading and talking.

- Psychiatric and psychological evaluations
A psychiatric evaluation may be helpful in ruling out other illnesses such as depression which can cause symptoms similar to Alzheimer's disease. Neuro-psychological testing can evaluate memory, reasoning, writing, etc.

Preparing for the assessment

On the day of the appointment, it will be useful to have the following information on hand. Writing this information down and be sure to bring it with you.

Things you will be asked:

What symptoms have been noticed?
When did they first appear?
How have the symptoms changed over time?
What other medical conditions exist?
What medications are currently being taken (both prescription and over-the-counter)?
What herbal remedies and/or dietary supplements are currently being taken?
Is there a family history of Alzheimer's disease or psychiatric conditions?

Things you may want to ask:

Which tests will be performed?
What is involved in the tests?
How long will the tests take?
How long will it take to learn the results?
How are the results communicated? Who will be involved?

It may be helpful to have a family member of a friend accompany you to appointments and tests. Think about who you would like to invite and talk about how they can help.

The family's role

Sometimes the person experiencing the problems will go to see her doctor. For others, the family will play a role in alerting the doctor of a problem.

Tips to lend a hand:

Make the appointment for the person
Help with transportation
Share this brochure with other family members
Offer to accompany the person to appointments and tests
Help prepare information for the first appointment
Appreciate that this can be an unsettling time for the person and provide emotional support
Have patience; it can take a long period of time to arrive at a diagnosis

If the diagnosis is Alzheimer's disease

You may want to ask:

What does the diagnosis mean?
What can be expected over time?
What care will be needed and is available, now and in the future?
What treatment is available? What are the risks and benefits?
What resources are available in the community to help?
Are there any experimental drug trials to participate in?
When is the next appointment?

Finding support

Please call us at 416-322-6560 at any time of the process for additional information, community referral or support.

Source: Getting a Diagnosis Alzheimer Society of Canada, 2009.

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